Computational model | The reversal potential for the excitatory and inhibitory inputs were 0 mV and -85 mV respectively. |
Introduction | To investigate this, we simulated an auditory cortical neuron using an integrate-and-f1re computational neuronal model [23—24] , and measured how changing the relative timing between excitatory and inhibitory inputs affected a neuron’s representation of temporal information. |
Methods). | 3), when either a synchronized neuron’s inhibitory input was reduced or a non-synchronized neuron’s excitatory input was increased, the neural coding regime changed to a mixed response (i.e. |
Methods). | We also hypothesized that the strength of a neuron’s inhibitory input would impact its temporal fidelity. |
Model parameters underlying rate and temporal representations | Mixed responses could occur when the excitatory input of a non-synchronized neuron increased in strength, or alternatively when the inhibitory input of a synchronized neuron decreased in strength. |