| Reversible assembly of large protein complexes can take tens of minutes | The average copy number of sequence—specific TFs per cell, as found in whole-cell proteomic studies, is around 2500 (S2 Fig), which results in a concentration of 3.5 nM [38—41]. |
| Supporting Information | Distribution of copy numbers were calculated for sequence specific TFs (blue), histone modifiers (green) and general TFs (red) based on the proteomic data from two mouse cell(line)s (Azimifar et al. |
| Supporting Information | The corresponding UniProt IDs lists were checked against the corresponding ID lists provided in the proteomic measurement publications and copy number measurements for proteins found used to calculate the distributions. |