| Discussion | Bow-tie can evolve for a nonlinear input-output relation too, if the input can be more compactly represented with no effect on the output. |
| Discussion | Here we considered the input-output relation as the sole force guiding the evolution of the network, however there may be other constraints or processes affecting network structures. |
| Simulations of multi-layered network models evolving towards input-output goals | In the linear model, the total input-output relationship of the network is given by the product of the matrices A1, A2,. |
| A phenomenological model | The composite model outperforms both the multiplicative and additive models, though less so when Ca2+ conductance is decreased by 75%, suggesting that the inability of the multiplicative and additive models to represent the input-output relationship depends on dendritic electrogenesis (Fig. |
| Discussion | In other words, the dendritic, spike-dependent manner in which tuft input changes the input-output relationship between basal input and frequency output is explicitly accounted for in the form of the composite equation. |
| Phenomenological model | We create three abstract models to describe the input-output relationship from tuft and basal excitatory input to firing rate output. |