Index of papers in March 2015 that mention
  • network-based
Francisco Martínez-Jiménez, Marc A. Marti-Renom
Discussion
The comparison of the nAnnoLyze method against the original AnnoLyze indicates that our network-based approach predicts drug-protein complexes with higher precision.
Discussion
Moreover, the network-based paradigm implemented in nAnnoLyze allows for the integration of other types of additional information such as the diseases linked to the protein targets, which may eventually allow for drug indication predictions.
Introduction
Others, named network-based approaches, exploit network properties to provide the drug target interactions and drug repositioning opportunities [11—18].
Introduction
Here we introduce nAnnoLyze, a network-based version of the comparative docking method AnnoLyze [23].
Network-based prediction of DrugBank ligand and human target pairs
Network-based prediction of DrugBank ligand and human target pairs
network-based is mentioned in 5 sentences in this paper.
Topics mentioned in this paper:
Yu-Chen Lo, Silvia Senese, Chien-Ming Li, Qiyang Hu, Yong Huang, Robert Damoiseaux, Jorge Z. Torres
CSNAP workflow
The most direct network-based scoring scheme is the neighbor counting method, where the annotation frequency in the immediate neighbors is ranked and assigned to the linked queries.
CSNAP workflow
Thus, the similarity between PPI networks and CSNs suggested that this approach could be effective for network-based drug target inference.
Discussion
In conclusion, we have developed a new network-based compound target identification method called CSNAP that can be used for large-scale profiling of hit compounds from chemical screens.
Target prediction of mitotic compounds from chemical screen
Target prediction accuracy comparison of network-based and ligand-based approaches.
network-based is mentioned in 4 sentences in this paper.
Topics mentioned in this paper: