| Characteristics of host proteins interacting with known B. mal/ei virulence factors | This protein, an interacting partner of BimA, has been implicated in the regulation of a large spectrum of signaling pathways [26]. |
| Human-B. mal/ei interactions and their effect on the crosstalk between different biological processes | It has been shown that a number of bacterial pathogens, including Yersinia, Salmonella, Shigella, Listeria, and Barkholderia, interfere with host signaling pathways to stimulate the host’s cytoskeleton rearrangement [2, 33]. |
| Human-B. mal/ei interactions and their effect on the crosstalk between different biological processes | The large number of signaling pathways affected via the |
| Multiple B. mal/ei virulence factors target eukaryotic-specific host-cell processes | These, in turn, are interconnected with a large number of signaling pathways (Fig. |