Type | peer-reviewed, open-access online journal |

Publisher | Public Library of Science |

Disciplines | Computer Science Biology |

Papers published in *PLOS Comp. Biol.* frequently mention these topics.

- 18 papers (16%) mention
- experimental data

- 14 papers (13%) mention
- standard deviation

- 13 papers (12%) mention
- gene expression

- 13 papers (12%) mention
- model parameters

- 12 papers (11%) mention
- firing rate

- 11 papers (10%) mention
- p-value

- 11 papers (10%) mention
- mathematical model

- 10 papers (9%) mention
- statistically significant

- 10 papers (9%) mention
- simulation results

- 9 papers (8%) mention
- time step

- 9 papers (8%) mention
- normal distribution

- 9 papers (8%) mention
- uniformly distributed

- 8 papers (7%) mention
- binding sites

- 8 papers (7%) mention
- E. coli

- 8 papers (7%) mention
- kinase

- 8 papers (7%) mention
- amino acid

- 8 papers (7%) mention
- sample size

- 8 papers (7%) mention
- network model

- 8 papers (7%) mention
- cell population

- 8 papers (7%) mention
- computational model

- 8 papers (7%) mention
- correlation coefficient

- 8 papers (7%) mention
- molecular dynamics

- 7 papers (6%) mention
- cell lines

- 7 papers (6%) mention
- ligands

- 7 papers (6%) mention
- transcriptional

- 7 papers (6%) mention
- cancer cell

- 7 papers (6%) mention
- parameter estimation

- 7 papers (6%) mention
- RMSD

- 7 papers (6%) mention
- steady state

- 7 papers (6%) mention
- confidence intervals

- 6 papers (5%) mention
- stem cells

- 6 papers (5%) mention
- spike trains

- 6 papers (5%) mention
- signaling pathways

- 6 papers (5%) mention
- free energy

- 6 papers (5%) mention
- immune response

- 6 papers (5%) mention
- neural networks

- 6 papers (5%) mention
- membrane potential

- 6 papers (5%) mention
- decision making

- 6 papers (5%) mention
- wild-type

- 6 papers (5%) mention
- regulatory network

- 6 papers (5%) mention
- maximum likelihood

- 6 papers (5%) mention
- crystal structure

- 6 papers (5%) mention
- parameter sets

- 6 papers (5%) mention
- MD simulations

- 6 papers (5%) mention
- substrates

- 6 papers (5%) mention
- genome-wide

- 6 papers (5%) mention
- decision-making

- 6 papers (5%) mention
- transcription factors

- 6 papers (5%) mention
- wild type

- 6 papers (5%) mention
- sensitivity analysis

- 6 papers (5%) mention
- differentially expressed

- 6 papers (5%) mention
- positively correlated

- 6 papers (5%) mention
- population level

- 6 papers (5%) mention
- feature selection

- 6 papers (5%) mention
- cell culture

- 5 papers (4%) mention
- input-output

- 5 papers (4%) mention
- mRNA

- 5 papers (4%) mention
- breast cancer

- 5 papers (4%) mention
- mutual information

- 5 papers (4%) mention
- gene set

- 5 papers (4%) mention
- neuronal activity

- 5 papers (4%) mention
- initial conditions

- 5 papers (4%) mention
- principal components

- 5 papers (4%) mention
- single cell

- 5 papers (4%) mention
- signaling networks

- 5 papers (4%) mention
- cell division

- 5 papers (4%) mention
- differential equation

- 5 papers (4%) mention
- experimental conditions

- 5 papers (4%) mention
- Hill coefficient

- 5 papers (4%) mention
- simulated data

- 5 papers (4%) mention
- fold change

- 5 papers (4%) mention
- t-test

- 5 papers (4%) mention
- force field

- 5 papers (4%) mention
- simulation study

- 5 papers (4%) mention
- biological systems

- 5 papers (4%) mention
- linear model

- 5 papers (4%) mention
- computational time

- 5 papers (4%) mention
- simple model

- 4 papers (3%) mention
- phosphorylation

- 4 papers (3%) mention
- cytokine

- 4 papers (3%) mention
- time series

- 4 papers (3%) mention
- cell cycle

- 4 papers (3%) mention
- growth rate

- 4 papers (3%) mention
- synaptic weights

- 4 papers (3%) mention
- cell-to-cell

- 4 papers (3%) mention
- ANOVA

- 4 papers (3%) mention
- functional connectivity

- 4 papers (3%) mention
- synaptic inputs

- 4 papers (3%) mention
- rate constants

- 4 papers (3%) mention
- age group

- 4 papers (3%) mention
- action potential

- 4 papers (3%) mention
- hydrogen bond

- 4 papers (3%) mention
- cell density

- 4 papers (3%) mention
- long-range

- 4 papers (3%) mention
- fixation point

- 4 papers (3%) mention
- feedforward

- 4 papers (3%) mention
- immune cells

- 4 papers (3%) mention
- crystal structures

- 4 papers (3%) mention
- predictive power

- 4 papers (3%) mention
- R0

- 4 papers (3%) mention
- meta-analysis

- 4 papers (3%) mention
- time course

- 4 papers (3%) mention
- drug target

- 4 papers (3%) mention
- learning rule

- 4 papers (3%) mention
- excitatory input

- 4 papers (3%) mention
- ICA

- 4 papers (3%) mention
- point mutations

- 4 papers (3%) mention
- tumor growth

- 4 papers (3%) mention
- cell growth

- 4 papers (3%) mention
- subpopulations

- 4 papers (3%) mention
- expression profiles

- 4 papers (3%) mention
- sequencing data

- 4 papers (3%) mention
- cell fate

- 4 papers (3%) mention
- Poisson model

- 4 papers (3%) mention
- Poisson process

- 4 papers (3%) mention
- time constant

- 4 papers (3%) mention
- cancer gene

- 4 papers (3%) mention
- upregulation

- 4 papers (3%) mention
- null model

- 4 papers (3%) mention
- active site

- 4 papers (3%) mention
- true positives

- 4 papers (3%) mention
- reinforcement learning

- 4 papers (3%) mention
- signal transduction

- 4 papers (3%) mention
- enrichment analysis

- 4 papers (3%) mention
- growth factor

- 4 papers (3%) mention
- expression data

- 4 papers (3%) mention
- AUC

- 4 papers (3%) mention
- binding affinity

- 4 papers (3%) mention
- false positives

- 4 papers (3%) mention
- microarray

- 4 papers (3%) mention
- kinetic parameters

- 4 papers (3%) mention
- generative model

- 4 papers (3%) mention
- cross-validated

- 4 papers (3%) mention
- Gaussian distribution

- 4 papers (3%) mention
- Fisherâ€™s Exact

- 4 papers (3%) mention
- RNA-Seq

- 4 papers (3%) mention
- choice tasks

- 4 papers (3%) mention
- energy barrier

- 4 papers (3%) mention
- brain regions

- 4 papers (3%) mention
- discovery rate

- 4 papers (3%) mention
- interaction network

- 4 papers (3%) mention
- steady-state

- 4 papers (3%) mention
- MATLAB

- 4 papers (3%) mention
- analytical results

- 4 papers (3%) mention
- linear combination

- 4 papers (3%) mention
- PSTH

- 4 papers (3%) mention
- dynamics simulations

- 4 papers (3%) mention
- molecular dynamics simulations

- 3 papers (2%) mention
- haplotypes

- 3 papers (2%) mention
- peptides

- 3 papers (2%) mention
- T cell

- 3 papers (2%) mention
- phylogenetic

- 3 papers (2%) mention
- power-law

- 3 papers (2%) mention
- lysis

- 3 papers (2%) mention
- SNP

- 3 papers (2%) mention
- optimisation

- 3 papers (2%) mention
- basal ganglia

- 3 papers (2%) mention
- MAPK

- 3 papers (2%) mention
- optimal control

- 3 papers (2%) mention
- adenocarcinoma

- 3 papers (2%) mention
- log-likelihood

- 3 papers (2%) mention
- simulated neurons

- 3 papers (2%) mention
- machine learning

- 3 papers (2%) mention
- power law

- 3 papers (2%) mention
- budding yeast

- 3 papers (2%) mention
- excitatory and inhibitory

- 3 papers (2%) mention
- cytoskeleton

- 3 papers (2%) mention
- coupling strength

- 3 papers (2%) mention
- basis functions

- 3 papers (2%) mention
- regression model

- 3 papers (2%) mention
- Bayesian model

- 3 papers (2%) mention
- feedback loop

- 3 papers (2%) mention
- eukaryotic

- 3 papers (2%) mention
- base pairs

- 3 papers (2%) mention
- branching process

- 3 papers (2%) mention
- in-vitro

- 3 papers (2%) mention
- HeLa cells

- 3 papers (2%) mention
- training set

- 3 papers (2%) mention
- effort costs

- 3 papers (2%) mention
- Hebbian

- 3 papers (2%) mention
- growth conditions

- 3 papers (2%) mention
- small molecules

- 3 papers (2%) mention
- likelihood ratio

- 3 papers (2%) mention
- synaptic connections

- 3 papers (2%) mention
- protein targets

- 3 papers (2%) mention
- proteome

- 3 papers (2%) mention
- cytometry

- 3 papers (2%) mention
- KEGG

- 3 papers (2%) mention
- Wilcoxon

- 3 papers (2%) mention
- destabilizing

- 3 papers (2%) mention
- Monte Carlo

- 3 papers (2%) mention
- log likelihood

- 3 papers (2%) mention
- SVM

- 3 papers (2%) mention
- PPI network

- 3 papers (2%) mention
- water molecules

- 3 papers (2%) mention
- de novo

- 3 papers (2%) mention
- learning algorithms

- 3 papers (2%) mention
- inhibitory inputs

- 3 papers (2%) mention
- cell death

- 3 papers (2%) mention
- protein-protein interactions

- 3 papers (2%) mention
- drug discovery

- 3 papers (2%) mention
- logistic regression

- 3 papers (2%) mention
- synaptic plasticity

- 3 papers (2%) mention
- AIC

- 3 papers (2%) mention
- connected component

- 3 papers (2%) mention
- probability distributions

- 3 papers (2%) mention
- linear regression

- 3 papers (2%) mention
- current injection

- 3 papers (2%) mention
- epidemiological models

- 3 papers (2%) mention
- posterior distribution

- 3 papers (2%) mention
- Bonferroni correction

- 3 papers (2%) mention
- Fisherâ€™s Exact test

- 3 papers (2%) mention
- cell differentiation

- 3 papers (2%) mention
- EM algorithm

- 3 papers (2%) mention
- immune system

- 3 papers (2%) mention
- allele frequency

- 3 papers (2%) mention
- X-ray

- 3 papers (2%) mention
- synergistic effect

- 3 papers (2%) mention
- estimation accuracy

- 3 papers (2%) mention
- Spearman correlation

- 3 papers (2%) mention
- false discovery rate

- 3 papers (2%) mention
- distribution function

- 3 papers (2%) mention
- real-time

- 3 papers (2%) mention
- network-based

- 3 papers (2%) mention
- Gene Ontology

- 3 papers (2%) mention
- input-output relationship

- 3 papers (2%) mention
- model simulations

- 3 papers (2%) mention
- cell cycle regulation

- 3 papers (2%) mention
- cycle regulation

- 3 papers (2%) mention
- high-throughput

- 3 papers (2%) mention
- energy difference

- 3 papers (2%) mention
- web server

- 3 papers (2%) mention
- prefrontal cortex

- 3 papers (2%) mention
- sequencing technologies

- 3 papers (2%) mention
- support vector

- 3 papers (2%) mention
- associative learning

- 3 papers (2%) mention
- case studies